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Monthly Archives: July 2015

A Lab That Cares

It can be difficult to find an opiate screening lab in South Carolina.  First and foremost, labs aren’t always listed with a single characteristic as their defining feature.  Most opiate screening lab options will come coupled with a number of other screening solutions; such as marijuana screening, or methamphetamine screening.  Most drug labs cater to a variety of different substance testing needs, so you’re not very likely to find a lab that just jumps right out and yells: “Opiate screening here!”

What you’re going to look for is a drug test laboratory that has good reputation and features the kind of services it should.  For example, in the modern era a good drug testing lab should offer an online portal to make requisitions for testing wherever there’s access to the internet.  Most such services also allow the client to view results on the web as well.  Also, an opiate screening lab option is necessarily going to be more specific than most lab screening options, so a professional lab will offer multiple protocols in order to accede to the needs of multiple markets.  Protocols worthy of the public will have been designed by experts in the industry in order that the entirety of the drug testing cycle is represented; this includes what manner in which specimens are collected, what kinds of tests are run on the specimens, and just how reports are formatted.  Such customizable protocols are par for the course at a good drug test lab, and what the client looking for a professional opiate screening lab should be watching for.

Immunoassay and LC/MS/MS technology is something professional labs are known for.  Look for provision of definitive analysis on a large variety of abused substances, and a report whose format is easy to read.  Also, ensure that the opiate screening lab you’ve chosen confirms the validity of its specimens.

One lab that has a deep passion for the work they perform and complete cognizance of its importance to clients and society in general is Premier Medical Laboratory Services (PMLS) of Greenville South Carolina.  With years’ experience in multiple kinds of substance screening, PMLS offers results that are fast and accurate, protocols that are fully customizable, and internet options for placing screening orders.

Finally, PMLS uses some of the most cutting-edge technology available in opiate screening labs.  MD Drug Pro is a drug monitoring program that is fully comprehensive and features testing capabilities that are superior and personalized.  Highly trained and experienced staff provide accurate and diagnostically meaningful tests that are consistent.  In fact, PMLS has through exceptional service and application found ways to add revenue to your practice that is substantial in measure.  Furthermore, medical compliance can be more responsibly monitored.

There are many different drug test lab options in South Carolina, but the best ones have the features emphasized in the precedent paragraphs.  Contact PMLS to save time and money, to customize complicated reports quantified through cutting edge technology, and to increase the safety of your premises.  For opiate screening lab options, PMLS is certainly one of the best.  Let their experienced and personable staff make your screening experience pleasant and less complicated, fully customized to your particular needs.

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Liquid Chromatography / Tandem Mass Spectrometry in Urine Testing Lab

Liquid Chromatography / Tandem Mass Spectrometry (LC-MS/MS) offers today’s best, and accurate urine testing lab results. It combines the advantages of two complementary techniques; Liquid Chromatography and Tandem Mass Spectrometry techniques. High-performance liquid chromatography fractionates the sample to individual analytes while tandem mass spectrometry quantities the analytes.

The fractionating phase is a critical factor to the method’s excellent analytical specificity. Beyond the regulatory necessity, doctors improve patient care by analyzing urinary drug concentrations. Close monitoring of urinary drug concentrations allows regulation of dosing regiments to show the varying metabolic rates on the particular patient, thus improving and personalizing care.

Advantages of LC-MS/MS technology

LC-MS/MS drug testing technology has the highest;

  • Selectivity
  • Sensitivity
  • Accuracy
  • Precision

Liquid chromatography/mass spectrometry offers an alternative drug testing approach that reduces off-line sample preparation needed in GC/MS because moderately nonvolatile compounds can be scrutinized.

With the right equipment, acceptable LC separations can be attained for the polar analytes such as alcohols, amines, and carboxylic acids. This characteristic ability to analyze a variety of compounds in a liquid phase renders LC an attractive laboratory method.

Choosing method for drug testing

There are four key factors to check when choosing method for drug testing:

  • Selectivity – The capability to tell between similar drugs. Similarities in the various drug’s chemical structure can cause false positives if you employ a drug testing method that has little selectivity.
  • Sensitivity – Is the gauge of the lowest drug concentration that can be precisely identified using the test.  The ideal testing technique can detect very low and very high drug concentrations. Low sensitivity causes false negative results. The least drug concentration that can be accurately determined is known as the cut-off.
  • Accuracy – A measure of the closeness of the test results to the real value. The accuracy of a drug testing technique is determined by the method of sampling, sample works up, analysis method, and data processing method.
  • Robustness and precision – The capacity of the testing technique to give reproducible results. The precision aspect is important in an extremely variable sample such as urine.

Testing procedure

Liquid Chromatography

Analytes flow through the carbon-based material (C18) packed steel tube. Compounds are separated in the Colum (a filter). The column has an 18 carbon chain that has a high affinity for drugs being tested and their metabolites, ensnaring them in the column.

The drug compounds are sequentially washed away from the filter as the organic solvent increases.

Figure (a) Different drug classes order

Mass Spectrometry

This aspect of testing uses three phases of separation, each occurring in a quadrupole (Q1, Q2, and Q3).

  • The drug compounds are filtered in the Q1 depending on their intact molecular mass, which is a chemical formula derived the number.
  • In Q2, the drug compounds are fragmented by using a cloud of gas that strikes the compounds and makes it break apart.
  • In Q3, the compounds’ fragments are analyzed based on their molecular weight. For all the compounds, we scrutinize two fragments that are unique to the particular drug.

The above process, triple quadrupole mass spectrometer, is known as the multiple reaction monitoring (MRM). The process reduces the likelihood of false positives occurrence to almost zero because each drug has its molecular mass (parent ion), reaction time and fragment mass (daughter ion). Further, the process of using filters eliminates the effect of complex sample components that cause inaccuracy in an immunoassay.

Figure (b) Multiple Reaction Monitoring

At Premier Medical Laboratory Services (PMLS), we offer best LC-MS/MS urine testing lab results in our complex reference laboratory. To get the most accurate and timely urine testing lab results, call 1-877-335-2455.

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Quality Laboratory Services

A drug test lab needs to have the professional chops to be worthy of investment.  Such professionalism naturally includes fast, accurate results.  The best labs also feature customizable protocols malleable in multiple areas; from the way in which specimens are collected, to the sort of tests run on them, to what sort of format options make up reports.  A professional drug test lab knows that varying clientele will have varying needs, and will work to meet those needs in as complete a way as possible.

An increasingly popular option in drug test labs is an internet portal which can be used to place testing orders online.  The entry system is customizable in order that even the most common tests can be properly handled.  Furthermore, the result center of many decent drug test labs allows real-time access to test results through websites that are secure.  Such measures allow doctors or physicians to swiftly and comprehensively treat patients while still in the office.  Medicine is often a race against time, and the more quick a testing service is, the better a practitioner can use their results to induce positive health.

Greenville South Carolina has one of the best drug test labs of the region–or the country, according to some accounts.  Premier Medical Laboratory Services (PMLS) is an exceptionally professional endeavor which seeks to provide comprehensive, swift service to any practitioner or even private individual who needs trustworthy drug test results, and fast.  Many drug test lab facilities are featuring new technology in their procedures, and PMLS is certainly one of those labs.  There is a cutting edge software called MD Drug Pro, which is a monitoring program that comprehensively checks for the presence of drugs.  Services can be personalized through MD Drug Pro, and experienced practitioners using the program intensify how comprehensive it is.  It takes training and experience to properly facilitate testing in a laboratory, and PMLS has this in droves.  It is their prerogative to show customers how additional revenue in substantial numbers could be added to a given practice or clinic.  Simultaneously, patients’ medication compliance can be monitored as well.

PMLS doesn’t just use immunoassay technology, they are also familiar in LC/MS/MS tech, which is used to provide a definitive analysis across a wide variety of substance abuse to pain management practitioners.  This information is provided in a format which is easy to read, and in addition the validity of a specimen is also confirmed.

The PMLS drug test lab looks for stimulants including amphetamines, methamphetamines, methylphenidates, MDA, or MDMA.  PMLS also tests for benzodiazapines, such as alprazolam, clonazepam, diazepam, lorazepam, oxazepam, or temazepam.  Illicit testing options include cocaine, heroin, marijuana or PCP.  Opiates tested for include codeine, fentanyl, hydrocodone, hydromorphone, morphine, oxycodone, and oxymorphone.  PMLS also tests for alcohol, barbiturates, buprenorphine, carisoprodol, ketamine, methadone, meperidine, propoxyphene, and tramadol.

In general, if it’s a substance that can be used or abused, PMLS has the ability to test for it and provide quantized results which aide in treatment and assessment of individuals that have been found using.  Also, there are sometimes situations where an individual is required to take a certain medication, and tests are necessary to determine whether or not that medication is too much or too little.

There are a variety of reasons medical practitioners and private individuals may need the services of PMLS, and so PMLS seeks to accommodate as many clients as possible, as professionally as possible, and as quickly as possible.  Contact PMLS today to see if your testing needs will find solution in their services.  Odds are PMLS will have an option that works.

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Customized Drug Tests Take Screening To The Next Level

Designed to screen for a specific substance or set of substances, customizable drug tests can be a practical way for employers to ensure workplace safety while respecting employee privacy. This type of testing can also be a valuable means of collecting data within a defined region or context, helping to identify and target specific drug trends or problems. Using customized drug tests can enhance the efficiency of pre-employment and post-hiring screening processes.

Balancing Safety and Privacy

While workplace safety is essential, what employees do on their days off isn’t always an employer’s business, not when it doesn’t have a measurable impact on job performance. There are many employees that resent the loss of privacy that come with routine drug tests, believing that their time off should be completely their own, As demonstrated by recent trends in marijuana legalization, opinions are changing and a growing number of people don’t think it fair that a couple of puffs of a marijuana cigarette while on vacation could result in a failed drug test and loss of employment.

Employers in states where marijuana has been legalized to one degree or another, for example, may not want to test for marijuana use, preferring to focus their drug tests on substances that are addictive and may have a negative impact on job performance and safety. Certain industries may focus their drug tests on the substances that tend to be high risk for that particular group, such as testing for the abuse of prescription medicines among health care workers or amphetamine use in the trucking industry. Using customizable drug tests is a great way to maintain that fine balance between workplace safety and employee privacy.

Collecting Specific Data, Monitoring Trends In Drug Use

Certain regions are associated with particular types of drug abuse, such as methamphetamine use in poor rural and suburban regions or heroin use in some inner-city areas. Customizable drug testing can be a valuable means of amassing accurate data, information vital to targeting problem areas or substances and making decisions concerning the best use of prevention and treatment resources. This types of drug testing also serve well as a pre-hire screening tool able to help reduce the chance of hiring a person who may put others at risk via their drug use and associated negative behaviors.

Affordable and Practical

Buying customizable drug tests online make this screening tool one that is affordable and practical not for just large and wealthy corporations, but also for small businesses. Buying online also puts this smart data collection tool within the fiscal grasp of researchers and social service organizations. Learn more about drug test customization options and what they can do for your organization today.

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Drug Screening Laboratories; Regulations and Drug Tests

Drug screening laboratories have been certified by human health department so as to receive urine specimen so as to determine presence of drugs. Additionally, the laboratories conduct validity tests of the specimens so as to be sure they have not been substituted or adulterated. You need to note that it is only those laboratories that have been certified by Health and Human services can participate in the program of DOT drug testing.

Regulations

As a laboratory participating n the DOT testing, you need to comply with the requirements that have been set. It is important that your lab be familiar with requirements in 49 CFR part 40 and you need to pay attention to processing incoming specimens.

You must do the following when you receive the specimen for DOT drug testing;
You should first receive one copy of the CCF and not more than that
HHS has guidelines that you then comply to when accessioning as well as processing the urine specimen
Inspect the specimen and CCF for flaws such as;
ID in CCF and specimen bottle do not match
Seal of the specimen bottle is broken or has been tampered with
Collectors signature and name are omitted from CCF
The urine in the bottle is not sufficient for analysis
When the specimen meets the required criteria, the findings that you get should be documented and stop the tests.
Once done report your findings
Drug tested

The drug screening laboratories test for following classes of drugs;

Phencyclidines
Opiate Metabolites
Amphetamines
Cocaine metabolites
Marijuana metabolites
The DOT specimens should not be tested for any other drugs other than these that have been mentioned above.

Cut off concentration for the drug test

This are usually indicated in nanograms per milliliter ( ng/mL) and you need to adhere to them as a drug screening laboratory.

Validity test

This is the evaluation of specimen so as to identify if it is consistent to what is considered normal human urine. This will help you determine if foreign substances or adulterants have been added to the urine sample, diluted or it has been substituted.

As a drug screening laboratory you need to conduct validity tests on the primary specimens. These tests include;

Determination of the creatinine concentration
pH
Conducting tests of one or several for the oxidizing adulterants
If you observe the following abnormalities you need to conduct more tests;

Physical characteristics of the primary specimen are abnormal
Response characteristic or reaction of adulterants that you obtained in the initial test
If there are adulterants or other substances interfering with the results and have not been identified
If you find that your specimen is invalid in relation to the guidelines under HHS
Criteria used to establish if a specimen is substituted or diluted

You can determine this as a drug screening laboratory when;

Creatinine concentration is more than or equal to 2mg/dL but is not more than 20mg/dL
Gravity of specimen is greater than 1.000 and less than 1.0030 in single aliquot
This must hold true for both the initial and confirmatory tests that you conduct on the primary specimen.

When you are through with the test, you will report the result you get for all the primary specimens. The results fall in two categories;

Negative results

Negative
Negative – dilute with specific gravity and creatinine specific numerical value
Non negative results

Positive with drug metabolite noted and values of the same
Substituted with confirming tests of specific gravity and creatinine specific numerical value
Adulterated with remarks
Invalid results – report the actual pH levels.

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Online Lab Testing for Accuracy and Convenience

Online lab testing will help you to order as well as get your results online. This is a recent addition to the health sector which is promoting more involvement of patient in their health. Due to their convenience and accuracy, online lab testing has become popular. When you use this service, you will be directed to one of the laboratories that have been referenced. They will direct you to collection sites for specimens or blood that has been requested.

As a client, you will need to first set up an account. When you decide on the test that you want such as drug testing, an order will be placed through your account. After a lab form is generated that indicates all the tests that have been ordered. Through the online testing service, you will be able to choose a collection site for your specimen and present the form that you have printed. Your lab results will be available in 24 – 72 hours. You can then download, save or store them in your private account.

The online lab testing services offer better ratings in the major clinical accredited referenced laboratories to perform tests. Accuracy of your tests results will be the same just like those that the doctor would have ordered. The internet based laboratory service is cheaper and the testing fees are lower than what you would be charged as a patient when your doctor orders the lab tests. Despite the fees that you are charged online are inclusive of markup, the total cost is less than when you are directly billed by the referencing laboratory.

Clinical reference labs will not allow you to order your drug tests directly. This is why online testing is more cost effective and convenient than the test your doctor orders. This is a good solution for you if you do not have a doctor /patient relation or your visit to the doctor is far from the time you desire to have the test.

Your online lab account is private and your results remain confidential. You can have a piece of mind especially if the tests that are being done are sensitive in nature. With millions of people scheduled to obtain private health insurance, it is important that you begin to assemble your health record if you are not insured. Online lab testing will be useful in gathering information which will be useful to your doctor in the future.

Online lab testing has gained strides with the ability to detect diseases and aid treatment. Additionally, it is a quick reference tool that will help doctors keep up with advances in lab technology. The information that is on the online lab testing can be used in the facilitation of consultations between the lab professionals and physicians.

Another important fact about online lab testing is that it has become the standard for patient education. It offers vital components that will improve engagement of patients and health literacy. Since it was launched, online lab testing has helped many to understand the tests as well as communicate with the physicians. Results are usually interpreted to the range of reference. This is why it is important to make important health choices about your lab results and medical tests. This will help you have healthy outcome in your patient care.

The methodologies that the online lab tests use vary and the way to determine the accuracy and convenience of the tests will be based on you.  You have a role in the process and it will help you in the preparation for your tests.

Families in Canada order more medicines per man than any other area. The variety of medications marketed by companies is no doubt a contributing matter to recipe medicament abuse epidemic. Various remedies are used to treat Bladder priming. Certainly it isn’t all. Kamagra is a preparation preassigned to treat many upsets. What do you think about http://levitra-cost.com/levitra-20-mg.html? When you order medications like Kamagra you have to remember about levitra 20 mg. More information about Kamagra available at levitra 20mg. Generally, both men and women are afflicted by sexual dysfunctions. At times another disease can cause to emasculation. Preparatory to purchasing Kamagra or other generic, speak to your pharmacist if you have any allergies. Talk to your soundness care professional any changes in libido you have experienced. Online pharmacy is a best way to find a doc in your area who treats this kind of dysfunction.