Heart Disease

Labs Like Premier Medical Laboratory Services Now Seeing Increased Demand for Various Molecular Diagnostic Tests

~As social distancing measures have decreased, demand for medical tests other than COVID-19 increase~

GREENVILLE, SC September 23, 2020  – At the onset of the pandemic the nation began to practice social distancing, and subsequently, many stopped scheduling visits with their doctors. Laboratories like Premier Medical Laboratory Services suddenly pivoted much of their efforts into providing a high volume of testing for COVID-19. Now, as more businesses and schools have reopened, less of the population has continued to practice extreme social distancing measures. Accordingly, more patients are visiting their physicians’ offices again for routine check-ups and other healthcare needs other than the Coronavirus.

With this, PMLS, recently named one of the Top Genetic Diagnostic Companies of 2020, says that they are beginning to see a rise in demand for tests that they offer to address various medical diagnostic needs aside from COVID-19. Some of these tests included are their pharmacogenomics, advanced cardiovascular testing, and their women’s health & wellness and diabetes panels.

“We are continuing to process up to 50,000 COVID-19 tests per day, but are glad to see an increase in orders for the other tests we provide,” said Kevin Murdock founder of Premier Medical Laboratory Services. “We know that our tests offer vital insight to physicians so that they can best plan the proper care for their patients.”

Including their portfolio of COVID-19 assays, all of PMLS’ tests processed at their 40,000 sqft laboratory are performed with the latest in science and technology to provide the most advanced and comprehensive testing results. For example, PMLS’s MDDiabeticPro panel includes the revolutionary DIABETESpredict test, which is a first of its kind predictive genetic test for type 2 diabetes developed in collaboration with world leading doctors and scientists of Harvard and MIT. The DIABETESpredict test is expected to mark a new era in diabetes prevention and care through evaluating the risk of the disease onset by examining individual genetic profiles and is currently only available to the US through PMLS.

PMLS’s cardiovascular panel, MDHeartPro, offers a more complete look at a patient’s cardiovascular health than the standard lipid profile that is commonly ordered.  In addition to the standard lipid panel, MDHeartPro includes tests that identify plaque buildup, lipid particle size, hereditary factors, and other advanced risk factors.

At PMLS’s fully COLA and CLIA regulated laboratory many of their processes are automated with cutting-edge laboratory equipment. Using a cloud based-laboratory information management system, OnGen, PMLS communicates real-time results to physicians directly from their lab equipment. Because of this, PMLS is able to process hundreds of thousands of COVID-19 tests per month while increasing the testing capacity for their other molecular diagnostic offerings without compromising accuracy or their quick turnaround time of results.

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What causes a stroke

Image result for stroke

A stroke happens when the blood supply to a section of your brain is reduced or interrupted thus depriving your brain tissues of nutrients and oxygen. If this continues for several minutes, your brain cells start dying. A stroke is a medical emergency that still kills people worldwide and should be treated with urgency. You can minimize potential complications and minimize brain damage if action is taken promptly. Knowing what causes stroke could be instrumental in treating and preventing a stroke.

Types of Strokes

There are two major ways in which a stroke can happen. One is caused when something causes bleeding in the brain and another when something blocks the flow of blood.

  • Ischemic Stroke

This is the most common type of stroke as it happens in 8 out of 10 cases of stroke. This kind of stroke happens when the blood vessel responsible for taking blood to your brain gets plugged. It also happens when there’s poor blood flow from an irregular heartbeat thus form a blood clot or when fatty deposits contained in arteries break off and move towards the brain.

  • Hemorrhagic Stroke

A Hemorrhagic stroke is less prevalent than an ischemic stroke although it can tend to be more serious. This type of stroke occurs when a weakened blood vessel in your brain leaks or when it balloons up and bursts. Taking too much blood thinner drugs and uncontrolled high blood pressure can also cause this kind of stroke.

  • Transient Ischemic Attack (TIA)

Some few individuals experience this kind of stroke usually referred to as a “mini-stroke” which happens due to temporary blockage. Although TIA doesn’t cause permanent brain damage, it increases your chances of getting a full-scale stroke

Top Causes of Stroke

The following things can put you at risk of getting stroke;

Tobacco – Whether you’re chewing or smoking tobacco, you raise your chances of getting a stroke. Nicotine is likely to increase your blood pressure and cigarette smoke (even secondhand) makes fat build up in the main artery of your neck. Other than that, it thickens your blood thus making it more likely to clot.

Diabetes – Most people with diabetes are overweight and have high blood pressure and both these are risk factors for stroke. You’re also more likely to have a stroke when you have diabetes since diabetes destroys your blood vessels. The injury to your brain is also likely to be severe if you get a stroke when your blood sugar levels are high.

High Blood Pressure – Also known as hypertension, this is the most common cause of strokes. You may need to consult your doctor if your blood pressure is 140/90 or higher.

Heart disease – Atrial fibrillation or irregular heartbeat and defective heart valves increase your odds of getting a stroke. In fact, irregular heartbeat is responsible for causing 25 percent of strokes among the elderly. Fatty deposits can also lead to clogged arteries.

Family – Strokes can be hereditary. Your family could be sharing a tendency to get diabetes or high blood pressure. As a matter of fact, some strokes occur due to a genetic disorder blocking blood flow to the brain.

Age – Anyone can get a stroke and that includes babies in the womb. However, your odds increase as you grow older. After you pass the age of 55, your chances double up every 10 years.

Gender – Men are more likely to have a stroke than women of the same age. But at a later age, women are less likely to recover and more likely to succumb to stroke.


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What Is the Main Cause of a Heart Attack

Established Accepted Research Facts

Previously, researchers reported in error that only 50 percent of heart attacks were caused by risk factors such as smoking cigarettes or unbridled cholesterol. But now they recapitulate that the cause of 90 percent of all heart attacks occur because of nine risk factors that you as an individual have the ability to avoid.

Before listing the nine beasts that form the main cause of a heart attack, you should read and mentally acknowledge that these risks are equal opportunity killers. They attack men and women, young and old, black, white, Asian, European and American.

You cannot reverse the dangers that two of the risks affect, so there is no escape hatch built into the human body. However, you can affect a decrease of risk by adopting a lifestyle of diet, exercise and moderate alcohol consumption.

Validating Study

Salim Yusuf, MD, leading cardio scientist for the above-referenced study, conducted the study of 30,000 patients, 50 percent being first heart attack survivors, and 50 percent being healthy volunteers comprising similar age, race and gender to the first group of heart attack survivor patients. The study was performed in 52 different countries and on every populated continent, and concluded that it is definite that the same factors of risk and heart dangers causing a heart attack in a white European also causes a heart attack in an Asian.

Compiled Risks Causing Heart Attack:

That last risk being abstaining from alcohol might be puzzling. However, scientific studies show males who drink up to two alcohol drinks per day, and females who drink up to one per day do have lower risk of heart disease. One drink is four to five ounces of wine, a 12-ounce beer or one ounce of liquor.

Measure Your Risk by Your Waistline

Instead of figuring the traditional body mass index, the study researchers took waistline measurements. A waist of more than 80 centimeters or 32 inches in women produced increased risk of heart attack. In men, a waistline more than 85 centimeters or 34 inches increased their heart attack risk. The waist measurement is a better and more accurate predictor because it is abdominal fat. That is the type far closely associated with heart attacks.

Summarizing Risk and Effect

The limits of your cardiovascular specialist and cardiologist to protect you from dying of a multi-infarct lie in their ability to provide you with latest scientific data, professional advice and a preventive treatment program. If prevention does not work and you suffer a major heart attack, your cardiologist will prescribe a more aggressive treatment plan. If that also fails, then a cardio surgeon might have an opportunity to participate in your treatment by arterial stent implantation or open heart surgery.

They cannot push the carbohydrates and fats off your fork and are unable to shove you into a gym or nature walk regularly. Their medical background is extensive and grueling, but requires your participation to be effective.

The road you take depends upon whether you choose to travel to prevention of a heart attack or take the highway to the major heart attack exit.

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What are Symptoms of Heart Disease?

Cardiovascular disease is an umbrella term used to describe a wide range of conditions that could affect your heart. It includes blood vessel illnesses like coronary artery disease, congenital heart defects (ones you’re born with) and heart rhythm problems (usually referred to as arrhythmias). In most occasions, the term “heart disease” is replaced with the term “cardiovascular disease.” Professionals define cardiovascular diseases as a general term for conditions that normally cause stroke, chest pain, or heart attack by either blocking or narrowing blood vessels. Heart disease can also be used to describe heart conditions affecting the rhythm, muscles or valves of your heart.

Symptoms of Coronary Artery Disease

Chest pain (scientifically referred to as angina) is the most common symptom of a CAD. If you have angina, you will experience squeezing, aching, discomfort, burning, or heaviness in your chest. Most individuals mistake angina with heartburn or even indigestion. The difference with angina is that you will feel it in almost all areas of your body including your throat, shoulders, back, neck, jaws, and arms. Other symptoms include the following;

  • Nausea
  • Shortness of breath
  • Sweating
  • Irregular heartbeats (palpitations)
  • Dizziness or weakness
  • Faster heartbeat

Symptoms of a Heart Attack

The following symptoms might suggest that you’re suffering from a heart attack;

  • Irregular/rapid heartbeats
  • Sweating
  • Nausea or vomiting
  • Indigestion, heartburn like feeling
  • Shortness of breath
  • Dizziness or extreme weakness
  • Heaviness, pain, or pressure in the chest
  • Anxiety
  • Discomfort in the throat, jaw, arm, or back

These symptoms can occur for around half an hour or even longer and may not respond positively to oral medication or bed rest. The symptoms might appear as mild but escalate to severe pain after a while. If you have diabetes, you’re likely to experience myocardial infarction (MI) commonly referred to as “silent” because it’s a heart attack that doesn’t manifest any symptoms.

Symptoms of Heart Failure

Heart failure may manifest through the following symptoms;

  • Weakness or fatigue
  • Rapid weight gain
  • Cough (with white sputum)
  • Irregular/rapid heartbeats
  • Dizziness, nausea
  • Chest pain
  • Shortness of breath
  • Swelling in legs and ankles

It’s important to note that these symptoms may not necessarily indicate that your heart is weak. Instead, they may just be a warning that your heart function is mildly weakened. However, it’s possible to have a heart that is severely damaged yet have few or no symptoms at all.

Symptoms of Congenital Heart Diseases

These are heart defects that may be discovered before birth, immediately after birth, during childhood or adulthood. Some people have these defects but experience no symptoms whatsoever. Such people end up being diagnosed through a chest X-ray or even a physical exam. Congenital heart defects among adults showcase the following symptoms;

  • Limited ability to exercise
  • Shortness of breath
  • Other symptoms of valve disease or heart failure

Symptoms of the disease among children or infants include;

  • Poor weight gain/ feeding
  • Inability to exercise
  • Bluish tint on the lips, skin, or fingernails (cyanosis)
  • Cyclical lung infections
  • Fast breathing

There are many other conditions categorized as heart diseases such as Pericarditis, atherosclerotic disease (affecting blood vessels), Atrial Fibrillation, valvular heart disease, heart infections, Arrhythmias (abnormal heart rhythm), and Heart Muscle Disease or dilated cardiomyopathy. All or most of these illnesses showcase similar symptoms.

Heart disease is very deadly and should be treated as an emergency. Heart diseases can be treated if detected early. Hence it’s crucial to consult a doctor as soon as you experience any symptoms to lessen the damage done to the most important muscle in your body; your heart. In case of emergences such as heart attacks, call 911.

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How Does Sleep Deprivation Relate to Heart Health

When it comes to sleep deprivation, you have to be careful. On one hand there are constantly more and more people who stress the ideas of productivity, efficiency, and even accomplishment to suggest sleep is not important. However, when you think about the actual facts and figures surrounding sleep and sleep deprivation then you can see how important it actually is to get a full night of rest. Consider the following few items and how important sleep can be for you to be at your fullest, especially if you have any sort of heart issues in your family or with you personally.

General Recovery

When people are asleep at night, then their body is doing less. You are obviously still alive and your entire system is still capable of doing things, but when your body goes into sleep mode at night then you get to rest because your body isn’t doing as much and doesn’t have to support as much. Your heart rate will slow, your major systems will relax, and you can spend a period of many hours just laying there while the rest of your body heals and repairs itself as you prepare for the next day. However, without having the chance to rest fully and be able to recover, then you could wind up injured and even the minor bumps and bruises won’t be able to fully heal. The worst part of this overall equation however, is that if you can’t sleep your heart will not ever get the chance to rest overnight. It will keep working overtime and can start to burn itself out from overuse.

General Body Shape And Weight Loss

One of the major side effects of having any sort of schedule is you can keep your body and eating habits in a normal and constant cycle. This usually means you will be more fit and more active, generally speaking. However, when someone is not on a normal scale then they can run into multiple problems as their body tries to adjust to the lack of sleep. When you don’t get as many winks overnight as you are ideally supposed to, you can wind up having a decreased and inefficient metabolism. This will lead you to carrying extra weight and looking down upon exercise as you simply don’t have the energy to participate.

Sleep Means Peace

One of the biggest things that people forget about is general irritability. When you start to consider someone with high blood pressure and general stress issues, you are thinking about someone who simply does not get enough rest in a given day. That is why if you are trying to find a way to keep blood pressure low, then you should consider getting rest and relaxation. The best form of which is sleep. The converse and not getting enough sleep would lead to higher irritability, less patience, and someone being more likely to blow up and become enraged. That would definitely not be good for heart and blood pressure regulation.

Whatever the specific reason you are looking for, the fact of the matter is you must sleep. And, because human beings can seriously run into some major problems if they aren’t able to sleep, you shouldn’t really be playing around with your system in that regard anyways. But, if you are going to cut back on sleep for one reason or another, then you need to be aware of the potential negative side effects and how not getting enough sleep could lead to some major problems within your cardiovascular system and within your heart overall as well.


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